abstract：:Follow-up studies have demonstrated that bronchiolitis caused by respiratory syncytial virus (RSV) is strongly associated with wheezing in the ensuing years. During the acute infection the immune response may induce long-lasting detrimental effects, thereby contributing to post-bronchiolitis wheezing (PBW). Therefore,...

journal_title：Pediatric pulmonology

authors： van Woensel JB,Kimpen JL,Sprikkelman AB,Ouwehand A,van Aalderen WM

更新日期：2000-08-01 00:00:00

abstract：:Impaired respiratory function has been found frequently in ex-premature children, but it is unclear which specific factors influence this impairment the most. The aim of this study was to determine the importance of the contributions of birth weight, gestational age, neonatal respiratory disease, and its treatment on ...

journal_title：Pediatric pulmonology

authors： Kennedy JD,Edward LJ,Bates DJ,Martin AJ,Dip SN,Haslam RR,McPhee AJ,Staugas RE,Baghurst P

更新日期：2000-07-01 00:00:00

abstract：:Tracheobronchomegaly (Mounier-Kuhn syndrome) is characterized by dilatation of the central airways, tracheobronchial outpouchings, and chronic tracheobronchitis. Most cases are diagnosed in adulthood. We report the clinical, radiographic, and bronchoscopic findings in a 14-year-old boy with tracheobronchomegaly, ptosi...

journal_title：Pediatric pulmonology

authors： Benesch M,Eber E,Pfleger A,Zach MS

更新日期：2000-06-01 00:00:00

abstract：:In adults, the term specific pulmonary renal syndrome describes disorders with pulmonary and glomerular manifestations and includes Wegener's granulomatosis, Goodpasture disease, and systemic lupus erythematosus. Nonspecific pulmonary renal syndrome refers to either pulmonary disease complicating glomerular disease, o...

journal_title：Pediatric pulmonology

authors： von Vigier RO,Trummler SA,Laux-End R,Sauvain MJ,Truttmann AC,Bianchetti MG

更新日期：2000-05-01 00:00:00

abstract：:A 14-year-old Korean boy was admitted with cough, hemoptysis, and fever. A chest X-ray showed a solitary pulmonary mass and pneumonitis. Bronchial biopsy by fiberoptic bronchoscopy revealed a poorly differentiated small cell carcinoma. All of the staging information indicated that the patient had limited disease. Duri...

journal_title：Pediatric pulmonology

authors： Kim CK,Chung CY,Koh YY

更新日期：2000-04-01 00:00:00

abstract：:The aim of this study was to compare safety and efficacy of bambuterol hydrochloride (10 mg) oral solution administered once daily in the evening with terbutaline sulphate (0.075 mg/kg body weight) oral solution administered three times daily in 2-5-year-old children with asthma. There were two treatment groups: (2/3)...

journal_title：Pediatric pulmonology

authors： Kuusela AL,Marenk M,Sandahl G,Sanderud J,Nikolajev K,Persson B

更新日期：2000-03-01 00:00:00

abstract：:Fetuses of diabetic mothers who were exposed to excessive glucose show delayed maturation. Under these conditions, altered growth factor expression or signaling may have important regulatory influences. We examined the role of epidermal growth factor (EGF) in lung development and maternal diabetes in the rat. In order...

journal_title：Pediatric pulmonology

authors： Thulesen J,Poulsen SS,Nexø E,Raaberg L

更新日期：2000-02-01 00:00:00

abstract：:Eight patients with cystic fibrosis [CF] colonized with Pseudomonas aeruginosa (P. aeruginosa) had serial lung function, peripheral blood inflammatory markers, and serum IgG antibodies to Burkholderia cepacia (B. cepacia) lipopolysaccharide measured in the months preceding and following colonisation with B. cepacia. O...

journal_title：Pediatric pulmonology

authors： Hendry J,Nixon L,Dodd M,Elborn JS,Govan J,Shale DJ,Webb AK

更新日期：2000-01-01 00:00:00

abstract：:This review summarizes current knowledge about the role of nitric oxide (NO) in cystic fibrosis (CF) lung disease. NO is endogenously produced by a group of enzymes, the NO synthases (NOSs). There are three isoforms of NOS, each encoded by different genes: neuronal (nNOS), immune or inducible (iNOS), and endothelial (...

journal_title：Pediatric pulmonology

authors： Grasemann H,Ratjen F

更新日期：1999-12-01 00:00:00

abstract：:Four patients with severe cystic fibrosis lung disease, anorexia and weight loss, received Megestrol Acetate (MA), as an appetite stimulant. The initial dose was 400-800 mg daily and was continued for 6-15 months. Appetite was improved, with significant weight gain in all patients and an increase in their weight for a...

journal_title：Pediatric pulmonology

authors： Nasr SZ,Hurwitz ME,Brown RW,Elghoroury M,Rosen D

更新日期：1999-11-01 00:00:00

abstract：:Congenital pulmonary venous stenosis (CPVS) has been previously described in older infants and children, typically manifesting as failure to thrive with congestive heart failure and subsequent respiratory deterioration. We report on 2 cases of CPVS which presented during the immediate newborn period as severe persiste...

journal_title：Pediatric pulmonology

authors： Holcomb RG,Tyson RW,Ivy DD,Abman SH,Kinsella JP

更新日期：1999-10-01 00:00:00

abstract：:Viral colds are an important cause of respiratory symptoms in normal children. Studies in adults suggest that inflammation in the lower respiratory tract is associated with viral colds, but there are no data regarding inflammation and viral infection in the lower airway of normal children with colds. We, therefore, st...

journal_title：Pediatric pulmonology

authors： Grigg J,Riedler J,Robertson CF

更新日期：1999-08-01 00:00:00

abstract：:The objective of this study was to determine the neurodevelopmental and temperamental outcome of infants who suffered an idiopathic apparent life-threatening event (IALTE) and their mothers' perceptions of such an event, and to compare such infants with a matched group of babies hospitalized for nonthreatening events....

journal_title：Pediatric pulmonology

authors： Tirosh E,Kessel A,Jaffe M,Cohen A

更新日期：1999-07-01 00:00:00

abstract：:A variety of postnatal therapies have been and will be evaluated for prevention or treatment of neonatal chronic lung disease (CLD). A simple method for early selection of the highest risk infants would optimize intervention trials. Our study compared a clinical scoring system for predicting neonatal CLD (defined at 3...

journal_title：Pediatric pulmonology

authors： Yoder BA,Anwar MU,Clark RH

更新日期：1999-06-01 00:00:00

abstract：:The aim of our study was to examine the effect of labor and birth canal compression on the rate of clearance of lung fluid. We recruited 10 babies born by vaginal delivery and 10 born by elective cesarean section (ECS). Thoracic gas volume (TGV) was measured using total body plethysmography, and functional residual ca...

journal_title：Pediatric pulmonology

authors： Lee S,Hassan A,Ingram D,Milner AD

更新日期：1999-05-01 00:00:00

abstract：:The free running test is a useful method for evaluation of exercise-induced bronchospasm in children. In young children this test simulates real-life circumstances and can be done more easily than histamine or methacholine challenges. The interrupter technique is a noninvasive method for measuring airflow resistance d...

journal_title：Pediatric pulmonology

authors： Kannisto S,Vanninen E,Remes K,Korppi M

更新日期：1999-03-01 00:00:00

abstract：:With dual energy X-ray absorptiometry (DEXA), it is possible to quantitate important aspects of growth in children with cystic fibrosis (CF), supplementing the usual measures of height and weight. Of particular concern during growth is the accumulation of bone mineral, since osteoporosis and fractures are well-recogni...

journal_title：Pediatric pulmonology

authors： Henderson RC,Madsen CD

更新日期：1999-02-01 00:00:00

abstract：:Standard chemotherapy for tuberculosis (TB) in children uses hepatotoxic drugs. Published data and guidelines on monitoring of liver function during TB treatment are often contradictory and not directly relevant to the pediatric population. We carefully monitored 43 children (age 6.6 years, 0.7-15.1 [median, range]; 4...

journal_title：Pediatric pulmonology

authors： Corrigan D,Paton J

更新日期：1999-01-01 00:00:00

abstract：:This study evaluates different ventilator strategies during gas (GV) and partial liquid ventilation (PLV) in spontaneously breathing animals. We hypothesized that during PLV, spontaneously breathing animals would self-regulate respiratory parameters by increasing respiratory rate (RR) and minute ventilation (V'E) when...

journal_title：Pediatric pulmonology

authors： Bendel-Stenzel EM,Mrozek JD,Bing DR,Meyers PA,Connett JE,Mammel MC

更新日期：1998-11-01 00:00:00

abstract：:Corticosteroids continue to be used by many physicians to treat infants with bronchiolitis. The aim of this study was to examine the short-term and long-term efficacy of oral corticosteroid therapy when added to beta2-agonists in infants with mild to moderate bronchiolitis (defined as the first episode of wheezing ass...

journal_title：Pediatric pulmonology

authors： Berger I,Argaman Z,Schwartz SB,Segal E,Kiderman A,Branski D,Kerem E

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVES:To determine 1) what proportion of abstracts of randomized controlled trials (RCTs) presented at international conferences on cystic fibrosis (CF) are published as full reports, 2) time to publication, and 3) factors that might delay or prevent publication. METHODS:At the end of 1995, the Cochrane CF Group'...

journal_title：Pediatric pulmonology

authors： Cheng K,Preston C,Ashby D,O'Hea U,Smyth RL

更新日期：1998-08-01 00:00:00

abstract：:In 1994-1995 a cross-sectional epidemiological study investigating the respiratory health of school children in two Taiwan areas was conducted; one area was located in a region with petrochemical manufacturing complexes (Linyuan), and the other was situated in a reference area with no local industrial emissions (Taihs...

journal_title：Pediatric pulmonology

authors： Yang CY,Wang JD,Chan CC,Hwang JS,Chen PC

更新日期：1998-05-01 00:00:00

abstract：:Our aim was to evaluate long-term effects of exogenous surfactant therapy on pulmonary functional outcome in children born very preterm. We examined 40 children aged 7-12 years who were born before 30 weeks of gestation with an immature surfactant system, and were randomized to one of three treatment groups: human sur...

journal_title：Pediatric pulmonology

authors： Pelkonen AS,Hakulinen AL,Turpeinen M,Hallman M

更新日期：1998-03-01 00:00:00

abstract：:Aerosolized recombinant human DNase (dornase alfa) reduces mucus viscoelasticity in vitro and improves pulmonary function in patients with cystic fibrosis (CF). We postulated that if dornase alfa could be delivered more peripherally to small airways in the lung in the form of smaller aerosol droplets in patients with ...

journal_title：Pediatric pulmonology

authors： Geller DE,Eigen H,Fiel SB,Clark A,Lamarre AP,Johnson CA,Konstan MW

更新日期：1998-02-01 00:00:00

abstract：:The aim of our study was to determine the effects of pulmonary vascular engorgement on airways and pulmonary tissues in juvenile animals before and after methacholine (Mch)-induced changes in lung function. Five anesthetized, paralyzed, and thoracotomized piglets were studied before and during pulmonary vascular engor...

journal_title：Pediatric pulmonology

authors： Wildhaber JH,Uhlig T,Sly PD

更新日期：1998-01-01 00:00:00

abstract：:The tidal flow volume (TFV) loop ratios of (1) time to peak flow (tPTEF) to total expiratory time (tE) [tPTEF/tE] and (2) volume to peak flow (VPTEF) to expired volume (VE) [VPTEF/VE] are reported to decrease with age in early life, and to decrease in subjects with obstructive airways disease (OAD). However, the mecha...

journal_title：Pediatric pulmonology

authors： Lødrup Carlsen KC,Stenzler A,Carlsen KH

更新日期：1997-12-01 00:00:00

abstract：:Previous research has demonstrated a significant reciprocal relationship between psychosocial factors and asthma morbidity in children. The National Cooperative Inner-City Asthma Study investigated both asthma-specific and non-specific psychosocial variables, including asthma knowledge beliefs and management behavior,...

journal_title：Pediatric pulmonology

authors： Wade S,Weil C,Holden G,Mitchell H,Evans R 3rd,Kruszon-Moran D,Bauman L,Crain E,Eggleston P,Kattan M,Kercsmar C,Leickly F,Malveaux F,Wedner HJ

更新日期：1997-10-01 00:00:00

abstract：:Although airway obstruction and chronic endobronchial infection have long been recognized as major factors in the pathogenesis of lung disease in cystic fibrosis (CF), only recently has it been recognized that the inflammatory process itself may be responsible in a major way for destroying the lungs. The most characte...

journal_title：Pediatric pulmonology

authors： Konstan MW,Berger M

更新日期：1997-08-01 00:00:00

abstract：:In cystic fibrosis the bronchiectatic conducting airways have large numbers of neutrophils in their walls and in their luminal contents. The neutrophil's primary granule enzyme activities of elastase and peroxidase are increased in the sputum of these patients. It has been postulated that these enzymes--together or in...

journal_title：Pediatric pulmonology

authors： Regelmann WE,Schneider LA,Fahrenkrug SC,Gray BH,Johnson S,Herron JM,Clawson CC,Clawson DJ,Wangensteen OD

更新日期：1997-07-01 00:00:00

abstract：:We have evaluated the role of eosinophil cationic protein (ECP) concentrations in serum in predicting wheezing after bronchiolitis, during infancy and early childhood. A prospective study at a university hospital serving all pediatric patients in a defined area was designed. Serum ECP concentrations were measured in 9...

journal_title：Pediatric pulmonology

authors： Reijonen TM,Korppi M,Kuikka L,Savolainen K,Kleemola M,Mononen I,Remes K

更新日期：1997-06-01 00:00:00

abstract：:Polyvinyl chloride (PVC) nasogastric feeding catheters are used clinically to measure intraesophageal pressure as an estimate of pleural pressure for calculating lung compliance in infants. The accuracy of pressure measurement of 4 French gauge (FG) catheter sizes and three brands of liquid-filled catheter manometer s...

journal_title：Pediatric pulmonology

authors： Hartford CG,Rogers GG,Turner MJ

更新日期：1997-05-01 00:00:00

abstract：:We compared the performance of selected ultrasonic and jet nebulizers when aerosolizing several antibiotic formulations to determine optimum combinations for delivery of a respirable antibiotic aerosol. Three ultrasonic devices were tested: the UltraNeb 99/100, the UltraAIR and the Aerosonic. The reusable jet nebulize...

journal_title：Pediatric pulmonology

authors： Weber A,Morlin G,Cohen M,Williams-Warren J,Ramsey B,Smith A

更新日期：1997-04-01 00:00:00

abstract：:Inhalation therapy for wheezy infants with either a nebulizer or a pressurized metered-dose inhaler (pMDI) through a spacer is common practice. The aim of our study was to compare aerosol delivery to wheezy infants from a nebulizer and from a pMDI via two small volume spacers. Twenty wheezy infants (aged 4-12 months) ...

journal_title：Pediatric pulmonology

authors： Wildhaber JH,Devadason SG,Hayden MJ,Eber E,Summers QA,LeSouëf PN

更新日期：1997-03-01 00:00:00

abstract：:Respiratory input impedance (Zin) is a potentially informative test of pulmonary function in infants who are unable to perform standard tests commonly performed in children and adults Analysis of Zin in dogs using the six-element model of DuBois et al. (J Appl Physiol 8:587, 1956) provides estimates of airways resista...

journal_title：Pediatric pulmonology

authors： Jackson AC,Neff KM,Dorkin HL,Lutchen KR

更新日期：1996-12-01 00:00:00

abstract：:There is a need to judge general exercise tolerance in children with cystic fibrosis (CF) under normal daily activity conditions and -when more extensive testing is required-in an exercise laboratory in a specialized center. We investigated the reproducibility, validity, and criterion for a 6-minute walking test, whic...

journal_title：Pediatric pulmonology

authors： Gulmans VA,van Veldhoven NH,de Meer K,Helders PJ

更新日期：1996-08-01 00:00:00

abstract：:Randomized trials of ribavirin therapy have used clinical scores to assess illness severity. Little information on agreement for these findings between observers has been published. We decided to determine interobserver agreement for (1) a history for apnea or respiratory failure; (2) assessment of cyanosis, respirato...

journal_title：Pediatric pulmonology

authors： Wang EE,Law BJ,Stephens D,Langley JM,MacDonald NE,Robinson JL,Dobson S,McDonald J,Boucher FD,de Carvalho V,Mitchell I

更新日期：1996-07-01 00:00:00

abstract：:We developed a simple method to identify neonates at high risk of bronchopulmonary dysplasia (BPD) and determined whether early (8 hours) and late (14 days) risk assessment is equally useful. A retrospective cohort design was utilized of subjects enrolled in multi-dose surfactant trials to develop each risk identifica...

journal_title：Pediatric pulmonology

authors： Rozycki HJ,Narla L

更新日期：1996-06-01 00:00:00

abstract：:We studied the left lung using multi-focus microphotography in 378 rat fetuses, assessing airway branching from day 13 to day 19 of gestation, and lung growth variables from day 13 to day 21. Longitudinal growth, and monopodial and dichotomous branching brought about a consistent airway pattern with variations within ...

journal_title：Pediatric pulmonology

authors： Rotschild A,Massoud EA,Solimano A,Puterman ML,Sekhon HS,Thurlbeck WM

更新日期：1996-04-01 00:00:00

abstract：:Increased numbers of eosinophils and increased concentrations of plasma proteins have been found in the airways of patients with mild asthma. We used an intact guinea pig trachea model to investigate the role of eosinophil peroxidase (EPO) in altering the function of the airway epithelial barrier. EPO in the presence ...

journal_title：Pediatric pulmonology

authors： Brottman GM,Regelmann WE,Slungaard A,Wangensteen OD

更新日期：1996-03-01 00:00:00

abstract：:Progressive lung disease in patients with cystic fibrosis (CF) is caused by thick secretions, which cause airway obstruction and subsequent colonization and infection by inhaled pathogenic microorganisms. Recently, recombinant human DNase has been shown to reduce the viscoelasticity of sputum in patients with cystic f...

journal_title：Pediatric pulmonology

authors： Eng PA,Morton J,Douglass JA,Riedler J,Wilson J,Robertson CF

更新日期：1996-02-01 00:00:00